Sue Thomas is a Deaf woman with the ability to read lips. She moves to Washington, D.C. to begin her new job as an FBI agent and discovers that her new job is not all it's cracked up to be. Due to an out-of-date directory, she accidentally vents her disappointment to Special Agent Jack Hudson, who is impressed by her honesty and tests her skills by having her read a colleague's lips, discovering he is planning a weekend away with a woman. Jack asks Sue to join his Unit of Special Investigators, where she discovers that her new friend Lucy is the girlfriend of Myles, the man Sue saw earlier planning a trip with a different woman.

Sue is put in the uncomfortable position of knowing that her new colleague Myles is having an affair behind his girlfriend Lucy's back while also trying to prove that, now that Jack has given her the chance of a lifetime, she has what it takes to follow through.

When Sue becomes an official member of the team, Jack trains her, and he has a perfect case for her: a bomb threat against a former FBI agent.

While trying to protect an Afghan leader, the team loses their primary assassin. But when they think that all hope is lost, another possible assassin is tracked down and put under surveillance, giving the team interesting results.

After Jack and Bobby arrest a drug dealer they, along with Sue, interrogate him in order to capture other drug dealers in the trade. Meanwhile, the rest of the team is focused on the brand-new offices on the fifth floor.

Having been handed a case about an infamous convict, the team tries to get closer to the convict through his partner, who is deaf.

Dimitrius gets a less than pleasant surprise when a man he had thrown in prison twelve years ago begins to spy on him and his family. Meanwhile, Lucy battles with a doctor who claims that her car dented the passenger door on his car.

In the middle of the Christmas season, a mysterious Santa was robbing banks with a few helpers. Bobby tries to present a good image to the press but a determined reporter is eager to attack the FBI. Sue's relationship with her mother comes to a head when her parents stay over.

A friend of Lucy's makes the team suspicious when a rumor begins to circulate that the large company that she works for might be going under. After work, the team heads to the football field, hoping to retain control of the infamous trophy.

After Bobby tries to protect a woman from an attacker, he is suspended from the FBI when the man turns out to be a Sudanese diplomat with immunity from US law enforcement. When the man is connected to a slave trade market, Darcy gets into some trouble of her own after she tells the public about the story.

The team races against time to find a crate of strontium which they believe will be used to make a dirty bomb. Lucy fears for her family when they are coming to her sister's wedding.

Drivers of two security trucks that were carrying money, go missing while on duty. While the team searches for them, Sue helps Lucy improve her sign language when the two go to a deaf club, where talking is not allowed.

When an unsuccessful raid by the FBI coincides with the disappearance of one of Sue's informants, the team believes that terrorists were the source of the leak. Eventually, it turns out that an aide to the Senator from Jack's hometown of Wisconsin was behind it.

The team's favorite waitress seems to be involved in software piracy and has been using Tara's business card in the process. Myles is then being considered a candidate for the new face of the FBI.

Trying to catch a long-awaited criminal, the team uses a jail-bound con man to capture him. The informant turns out to be Bobby's father, and Bobby is unhappy.

Sue goes on an FBI and DEA task force. Has love hit Levi and Sue? Charlie and Troy try to fix something at Lucy and Sue's apartment.

Sue meets Logan Taylor who says her dad helped catch the hunter Jerome Soggins in the 80's and tells Lucy, Sue and Charlie (who asked Sue for help in solving the case) that her dad told her that the wrong man was convicted. Jack has to give a deposition to clear his name of killing the chicken. Myles & Sue talk to Jerome who was convicted of two murders and had hoped Ben Taylor would clear his name and request a DNA sample and hope to match Jerome's DNA with the old evidence. Sue Myles look for cab drivers picture with an ""X"" drawn through the picture. Darcy tells Sue Myles and Bobby that the hunter wrote to a reporter but the letters were sold to someone. Logan learns that her dad did love her by keeping letters and pictures. Tim reads Darcy's article on the hunter case which leads him to think his dad is the hunter and says his dad was violent man and would recall seeing his dad clean himself up. Sue & Myles talk with Kenneth who admits to killing some of the cab drivers but not the

Sue is asked by someone from high school to attend her wedding, One problem Sue's friend made fun of her. Sue and the gang have to find 5 prisoners that escaped after a prison van and semi truck crashed. As the gang looks for Jed they find that Wendy Stack testified against him because of abuse to wonder why she would visit him after the trial. The team finds out that evil Jed passed through a choke point to keep from finding the diamonds. As the wedding date for Sue's friend draws near Sue doesn't want to have old feelings of how she was treated to come back. Jack tries to cut a deal with someone to find Jed. Sue learns that David can't go to the wedding to attend a flower show. Sue is picked on at the weeding by someone who thinks Levi is a seeing eye dog after Sue explains Levi is a hearing dog. The football player finds out after visiting Sue that he should have stopped people from picking on her and the growing up can be hard to do.

Lucy gets worried about a man who has fallen in love with her mom, Jack's mentor is shot which leads Jack to wonder if the discovery about the drug labs had anything to do with the death of his mentor.

Sue meets Amanda, who tells her she saw a kidnapping. Everyone has trouble believing the story except Sue. Sue first met Amanda at Career Day some years ago. Myles meets Nora who wants to write a book on him. Sue learns someone died of Ricin poisoning by Castor Beans. To make sure her story is true, Amanda see the kidnappers again (after sneaking out of her home) she plants a tracking device. Tara gets a note that terrorists know where Amanda lives, Amanda's dad wants help in communicating with Amanda. Myles gives Nora an idea for her book, she wants to focus on Amanda and get to know Myles.

The gang gets word of another shooting making this attack the third one in two days. Jack tells Sue that he was a Sniper before working for the FBI. Sue then gives Jack a report that tells only about the barrel of the gun used but not the type of gun used. Just as Jack goes to rest he learns the Mayor was shot. When Jack gives a press conference he gets the idea to make himself a target in hopes catching the sniper. Sue goes to the dance with David, but Jack doesn't want Sue to worry about the case.

Sue thinks something is wrong with Charlie, when he doesn't remember needing to change the oil in her car. Sue changes her mind as to what she thinks is wrong with him when Charlie tells her he had to get rid of some things his late wife owned. Troy thinks Charlie may have a hearing problem, because Troy had seen Charlie yell at a customer. In order to find a suicide bomber Bobby & Sue meet a hacker who was told to hack websites on a dare.

The Boys are apart of an online bachelor auction, soon Myles gets the most bids for charity. Sue tries to honor a dying mother's wish, to find out who killed her daughter Julie. The FBI talks to Brian Cooper who killed Julie because she helped rob the bank. Sue learns that there is sometimes a limit to how much justice is allowed by law.

To solve there latest case Jack & Sue pretend to be a married couple. They need to find out why Joseph and Betty are funding terrorist acts. Sue meets Betty and learns she donates time to service dog charities. They try to come up with answers to questions Joseph & Betty might ask. As Sue tries to read Joseph's lips, Jack finds himself in love with Sue. Jack learns Sue is a great cook. Levi also falls in love. Miles hurts his car while tracking Joseph. The man Sue & Jack are tracking is assuming a dead man named Joseph who died in 1996 of a heart attack. Myles learns that one of the Virginia College students is planning to spread Bubonic Plague all over Washington D.C.

The FBI worries that an upcoming march could be the target of a possible terrorist attack. Sue tries to enlist Betty's help in trying to capture her husband. Jack and the gang find where the Bubonic Plague was stored and how Joseph maybe spreading it. As Betty learns more about her husband she understands that Sue was right about him.

Tara decides to get her hair done, but soon a robber holds up the salon. Tara tries to go about business but has trouble dealing with what happened. Tara wonders if she should leave the FBI because she shot someone for the first time. Amanda (Sue's friend) finds a lost dog and wants to keep it.

Sue gets a taste of political life in Washington when she meets a congressional aid named Paul Minton, Sue looks into the past of Liz Bradley who was a Journalist. Sue questions Brian (who liked Liz) he says he shot her. Brian's Sister Shelly believes he was setup. Sue gets mad when the ad she made tells people who to vote for. Sue and Jack discover why Brian couldn't have killed Liz Bradley.

A woman offers Jack, Sue & Bobby someone big Johnny ""Red"" Moreno who laundered money through KBJ investment group through a poker game. Bobby risks his job to get the bad guy. Sue and Lucy try to figure out why Levi is acting oddly. Sue and Lucy learn that Levi's Flee medicine is making him act odd. The next day Levi takes the wrong pill leading him to act strange and force sue to continue to live her life without Levi after he runs away.

Sue helps look for Katie who was kidnapped from Gallaudet University. Sue & Jack question Lance who says he didn't kidnap Katie. Sue & Jack don't believe the story. Sue learns that Katie was adopted and found her biological mom after 19 years.

Lucy's Grandmother stops by with bad news. Mrs. Dotson will need to leave home and pay $110,000 to have them fixed. Lucy, Sue and Jack plan to stop Concove Construction by moving into a house the document as needing no repairs making Sue the homeowner and pay for repairs she can't afford. Lucy comes home to the smell of smoke leaving Lucy and Sue wondering why they smell smoke. Alice (Lucy's Grandmother) thinks the oven caused the smoke. In other news Levi lost his little companion Bunny in the end they cant find it so the F.B.I chip in to get Levi a new Bunny.

The team tries to stop a terrorist attack on Washington D.C. As Jack tries to stop the Al Qaeda leader, he learns that his methods come into question when a Civil Rights complaint is filed against him.

When an acquaintance of Sue sees who she thinks was a concentration camp guard in World War II, Sue begins to investigate, looking for the man with little evidence to go on. Meanwhile, Myles, Bobby, and Dimitrius battle against Randy over travel expenses.

Sue meets Jack and Bobby's FBI Mentor when he brings the team in on a case to sting a North Korean terror group - but Sue discovers that things are not as they seem. Meanwhile, Lucy reconnects with her old high school love - with surprising results.

Sue and Dimitrius put an operative in the field to take down an illegal arms sale - but when the encounter gives them a chance to land an even bigger fish, Dimitrius goes undercover as the bait. Meanwhile, Dimitrius' wife Donna has some unexpected news of her own.

Sue and the team must infiltrate a Chinese drug-smuggling ring, requiring Bobby to go undercover at the gang leader's nightclub - as an Elvis impersonator. And Sue learns that her friend Troy has an estranged brother - and that the estranged brother has a secret.

When the members of a think tank are found shot dead, Sue and the team track down the sole survivor - but is he a possible future victim or the murderer? By accident, Sue ends up in the fleeing man's car. And Sue teaches Levi some new tricks - or maybe he's teaching her.

Investigating a 5-year old murder, the team automatically links the killing to a group of drug dealers, but further investigating draws them towards another killing that occurred just months before the first. Meanwhile, Myles attempts to improve his neighborly relations.

In order to solve a case involving two men shot with the same gun, Sue and Jack go undercover to the law firm that the two men both worked at. With Myles' sister also working at the law firm the agents get deeper and deeper into the facts of the case.

When the F.B.I's special assistant Howie claims to have nearly escaped being shot, Jack and the team are skeptical as to the legitimacy of Howie's story. However Howie's tale becomes more and more plausible as other killings arise, all linked to Howie's incident.

Seven Eastern-European terrorists in the D.C area are under suspicion from the F.B.I team who have linked them to an underground organ dealing business. In the meantime, Sue and Lucy struggle to live with Anita, their unannounced, and very picky, house guest.

When a radical environmentalist group blows up an SUV dealership, the team looks into the case with the help of a victim from one of the environmentalist group's earlier fires. Meanwhile, with his cholesterol off the charts, Myles decides to make some changes to his dietary lifestyle.

A special undercover agent from San Diego comes to D.C to assist in an operation involving street drug dealers. But Jack quickly becomes annoyed with the new agent when he starts to show interest in Sue.

A famous actor visits the F.B.I to observe as the team tracks down a gang involved in selling fire arms. Later when the team gets word of a possible terrorist threat, the movie star begins to show interest in Tara.

The team continues their investigation concerning a missing plane which seems to be connected to their terrorist threat. Meanwhile, an unexpected boyfriend of Tara's shows up.

When several 30-year-old women are murdered in a similar fashion, the FBI team suspects a serial killer. At first, their chances of catching the killer seem bleak, but then the murderer makes contact with Sue and leads her through his own game of Simon Says which will lead them all to him.

Sue runs into an old friend at a deaf and poetry reading. Sue invites Carol to spend time with her and Lucy. Her husband Ted who is a financial money manager keeps Carol from spending time with Sue and Lucy. Leaving Lucy and Sue to wonder if everything is OK between Carol and Ted. Bobby and Myles have the displeasure of escorting Howie and Otis to a case out of town because they are informants in the case. As Bobby and Myles continue on their way to Arizona they learn something about Howie. He won't go to Arizona by plane because of his fear of crashing the plane so that forces Bobby and Myles to drive to Arizona. Tara and Lucy learn that Carol wasn't telling them whole truth. They find out that Ted made a lot of money. They also learn Carol had markings consistent with spousal abuse before, leading Sue, Lucy, Jack, and Tara to believe Carol pushed husband off the boat.

Sue and the team get a highly sensitive case to solve. Senator Fenton requests that the death of his son Kyle be looked into. He tells the team that his son died due to drinking himself to death fraternity initiation. The medical examiner's report on Kyle rules out alcohol poisoning but states that he was allergic peanut oil. Now the team is looking at a homicide and not a simple hazing. Also Sue and Lucy let Amanda stay with them for the night they get an idea of what parenting is like. As the help Amanda deal with going on a date and then being rejected at school. Amanda gets a harsh lesson to learn. She finds out that friends are hard to come by because she is deaf.

Sue and Jack receive a memory stick with some interesting video of to man possibly plotting something. Sue and Jack set out to meet the couple that bought the memory stick to the FBI. When Sue and Jack go the hospital to meet Jonathan they soon have a problem. Johnson is asked to look at a picture of to man and see if he recognizes them, Jonathan unfortunately can only remember his name and nothing else. Jack takes Jonathan to places to see if he can remember anything. Jack takes him to a restaurant and a certain table but the only thing he seems to remember is how to someone to the ground. Jonathan tells Jack that he can't remember where he learned those particular moves. The team takes Jonathan to his hotel room to see if he can remember why he was there. As they begin to search through the mysterious man's belongings they find a suitcase full of money and a gun with a silencer on it and several passports with Johnson's picture on them. They learn that of the fake passports c

We last left the story with Jack and Jessica running into each other in Washington D.C. for the first time. Jessica tells the team that Jonathan wasn't going to be found unless he wanted the team to find him. The team is led to believe that Jonathan killed Mr. Wells and took the hard drive out of his computer. Things only begin to get crazy as Jonathan begins to remember things. Sue gets a message on her blackberry indicating Jonathan would like to talk with her about some things he has remembered. He tells her he remembers seeing a car with license plate. As Sue tries to get more information the team is tracking Jonathan to office building. Jessica gets rather angry when the team loses Jonathan due to his escape from the office building just as he was about to remember something more. Tara begins to discover something interesting about Mr. Wong files that indicates a patriot missile targeting system.

The team tries to figure out why restaurant was blown up by a bomb. As they continue to investigate this discover that Danny is lying to protect his father. They learn that Danny's father works for an organization linked with a terrorist organization.

Sue hears about two women who've died because of a cult called the mind profit. Sue tries to help a young woman named Lily get to know her parents better after they began noticing strange behavior in their daughter. Lilly's parents tried to kidnap Lily said she wouldn't go back to Mind Profit. Sue investigates mind profit and tries to find her self. Sue begins to ask Lily about the dead women. Malcolm Hayden begins to think Sue knows too much and kidnaps her.

Randy makes an odd request of Sue. He asks her for some help with woman he is about to meet there is one problem in the correspondence Randy and his date have shared over the computer she forgot to tell Randy she was deaf. Sue now has to accompany Randy on his date to help him with the sign language.

Jack runs into a bounty hunter named Joe who used to work at the FBI until his daughter died. He blames Jack for his daughter's problems. Although the team searches for Fantasia (a new designer drug) Levi learns that he will grace the box of the latest dog food only to learn that it isn't so easy to do. Sue and Lucy begin the have problems with the photographer that has chosen to photograph Levi. Sue and Lucy learn that Levi will have to compete with the photographer's dog in order to be included in the latest dog calendar.

Sue learns that Troy is being blamed for armed robbery. Sue and Jack set out to prove whether he was part of the armed robbery or not. Darcy has gotten a job in Los Angeles and asks that Bobby go with her to Las Angeles. Bobby and his girlfriend both realize that they've each made the decision regarding Darcy's news. Bobby and Tara begin a relationship with each other. They soon find out that they have lost their love for their respective partners. Troy insists that he didn't do anything in the armed robbery. Sue tells Troy she believes him. Troy insists that he didn't do anything in the armed robbery. Sue tells troy she believes him. After the FBI learns of new video of the armed robbery Sue finds out Troy misled her because he is in the video.

Sue meets a woman who says she saw a murder but the only problem is there are sure whether Beth heard or saw the murder. Sue and Jack find out that their witness is schizophrenic and gives them clues in strange metaphors making the case all the more complicated to figure out. Also the team gets a new acting supervisor named Wayne. Their new supervisor begins to drive them crazy when one begins to color code all their cases. He places the current case as a low priority case. They soon find out that Wayne has never even solved an FBI case in his life.

Sue and the team investigate a bank robbery but this bank robbery becomes a little more interesting than the team expected. They find out that the bank they are investigating was robbed several years earlier. This time they learn that three girls have robbed the bank, which begins to seem strange to the team. When they robbed the bank they stole shoulder pads and one of the girls is the daughter of the president of the bank that was being robbed. Lucy has a mystery of for a long to figure out after her grandmother gives her a jewelry box. When the team opens the box to find out what it contains they are all very surprised at what falls out of the box. Lucy learns that the letters her grandmother kept were from her first love named Oscar. Sue and Lucy decide to track down Oscar because he still wants to see Lucy's grandmother. Lucy is shocked when her grandmother learns of her surprise.

In the series finale Sue Thomas gets promoted to senior investigative analyst for the F.B.I. Sue is thrilled with the promotion but soon realizes that heading to New York City would mean leaving her friends. Jack becomes a victim of identity theft and feel sad when he learns of Sue is promotion. While trying to catch the person who's committing identity theft Jack realizes that he was almost shot at and might never have gotten to say goodbye to Sue.